Sotalol is a non-selective, hydrophilic beta-blocker that prolongs cardiac repolarisation independent of its antiadrenergic action, thus representing class III antiarrhythmic effects.21 Skeletal formula of propranolol, the first clinically successful beta blocker. Class identifiers; Synonyms: β-blockers, beta-adrenergic blocking agents, beta antagonists, beta-adrenergic antagonists, beta-adrenoreceptor antagonists, beta adrenergic receptor antagonists Sotalol tablets are available in several different strengths: 40 mg, 80 mg, 160 mg and 200 mg. Each time you collect a fresh supply of tablets, it's a good idea to check the strength on the packet to make sure they are the strength you are expecting. Sotalol is a non-selective beta-adrenergic receptor blocker which has both class II and class III antiarrhythmic properties. [2] Sotalol was first described in 1964 and came into medical use in 1974. [4] Sotalol is a beta-blocker that affects the heart and circulation (blood flow through arteries and veins). Sotalol is used to help keep the heart beating normally in people with certain heart rhythm disorders of the ventricles (the lower chambers of the heart that allow blood to flow out of the heart). He showed doses needed to be increased in 18% of the β-blocker and 10% of the Sotalol group, the final doses being 54±14 mg Metoprolol group and 40±0 mg in the sotalol group. Medications were stopped in 1 patient per group. Selected Beta-Blockers/Selected Calcium Channel Blockers Interactions. This information is generalized and not intended as specific medical advice. Find patient medical information for Sotalol Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Find here the beta blocker Sotalol and its application in high blood pressure (hypertension) explained. describes the blood pressure and related beta blockers like Sotalol. 1.1 Life-Threatening Ventricular Arrhythmias. Sotalol Hydrochloride Tablets are indicated for the treatment of life-threatening, documented ventricular arrhythmias, such as sustained ventricular tachycardia (VT).