Usual Adult Dose for Hypothyroidism. Dosing should be individualized with consideration given to age, cardiovascular status, concomitant medical conditions (including pregnancy), and specific nature of condition; follow clinical response and laboratory parameters closely as dose is adjusted: I had my thyroxine increased 25mg to 75mg in total way back in August. I still feel rotten, no energy pain and tingling in hands and pain in feet,weight gain, tired moody, low and fed up of feeling rough. Then make sure you are on the right dose! Your dose should be based off of the 3 step system I outlined above: Lab tests, symptoms, and your metabolism. You can get to this dose by starting out with a low dose (around 25mcg per day) and then slowly increasing your dose and monitoring each of the steps. to get and keep your thyroxine dose right, you should be able to keep your hypothyroidism well controlled throughout your life. Your symptoms should disappear and the serious effects of low thyroid hormone should improve. If you keep your hypothyroidism well-controlled, it will not shorten your life span. WHAT CAUSES HYPOTHYROIDISM? There can be many reasons why the cells in the thyroid gland. Once you are on the right dose of levothyroxine, side effects should go away. Common side effects The common side effects of levothyroxine usually happen because the dose you're taking is more than you need. Getting the Right Dose of Thyroid Medicine - HealthgradesGetting the Right Dose of Thyroid Medicine; you must have the right you may need to increase your thyroxine dose temporarily to keep up with the extra demands Making the Most of Your Hypothyroidism Treatment Making the Most of Your Hypothyroidism Treatment. get your medication right and. The dose will then be increased by 25 micrograms every 2-4 weeks until your child shows mild symptoms of hyperthyroidism (a condition where the thyroid gland produces too much thyroxine). The dose will then be reduced slightly. Although our patients are not in a starving state, the higher thyroxine dose/kg in lower BMI patients may be due an impairment of T4 conversion (30,32,33). While the increased prevalence of thyroid disease among older women is well known, age as a predictor for LT4 dosing is debated (16, 18, 20, 201, 37). This is after 16 months of working on the right dose dose for me. I have to think that I am the exception to the rule and not that many people have the T4 to T3 conversion problem that I do. I have to think that I am the exception to the rule and not that many people have the T4 to T3 conversion problem that I do. How to use L-Thyroxine Tablet. Read the Patient Information Leaflet if available from your pharmacist before you start taking levothyroxine and each time you get a refill.