1 Dr. Friedman’s Guide to Estrogen Replacement There are risks and benefits with all medicines and estrogen replacement is no exception. Bioidentical progesterone with phytoestrogens The progesterone cream, AllVia Progensa Plus has been recommended by more holistic doctors than any other. Estrogen not deserve its bad reputation. Our endogenous estradiol is a powerful and highly beneficial steroid for metabolism, mood, sleep, and libido. So it would make sense to supplement progesterone if you are experiencing any of these. Quite often, just adding progesterone will restore normal balance and make a world of difference in how you feel. Estriol, the Safest Estrogen. Estriol is a Safe and Effective Hormone for Menopausal Women with Hot Flashes and Vaginal Dryness. Estriol is a type of estrogen made by the ovaries. Postmenopausal Women and Estrogen Estrogen levels decline at menopause, but not to zero. Estradiol falls generally to about 15 percent of premenopausal levels, and estrone falls only 40 to 50 percent of premenopausal levels. This is a matter of some controversy amongst different professionals. We can start by acknowledging that there is no agreement on this, no research that says one or another is the right choice for everyone. Route/form Estrogen Cancer Dosage Oral Estradiol Breast 2–10 mg 3x/day Prostate 1–2 mg 3x/day Conjugated estrogens Breast 10 mg 3x/day Prostate 1.25–2.5 mg 3x/day Ethinylestradiol Breast 1–3 mg/day Prostate 0.15–2 mg/day Ethinylestradiol sulfonate Prostate 1–2 mg 1x/week Diethylstilbestrol Breast 5 mg 3x/day Prostate 1–3 mg/day. Estradiol valerate (EV), sold under the brand names Delestrogen, Progynon Depot, and Progynova among others, is an estrogen medication which is used in hormone therapy for menopausal symptoms and low estrogen levels in women, in hormone therapy for transgender women, and in hormonal birth control for women. Estriol is one of the three main estrogens made in a woman’s body. The other estrogens are estrone and estradiol. Estriol may be used alone or in combination with the other estrogens in a number of different dosage forms, and has been shown in studies to have good activity in the vaginal area.