Nexium was bad news for my LPR (laryngeal pharyngeal reflux) treatment. I had not suffered heartburn and it was my allergist who made the diagnosis after I explained.Looking online for side effects, I learned Nexium was the culprit!. While most people with LPR reflux during the day, the worst cases are due to nighttime reflux. At night, all of your anti-reflux defenses slow down, which is why reflux causes more damage. At night, all of your anti-reflux defenses slow down, which is why reflux causes more damage. Laryngopharyngeal Reflux (LPR) Laryngopharyngeal reflux is a condition in which acid that is made in the stomach travels up the esophagus (swallowing tube) and gets to the throat. Symptoms include sore throat and an irritated larynx (voice box). Hello, I was diagnosed by LPR (Laryngopharyngeal Reflux). I would love to discuss managing of my LPR with other LPR sufferers. However, I can't find any active support group, forum etc. Gastroesphageal Reflux (GERD) & Laryngopharyngeal Reflux (LPR) What is GERD? Gastroesophageal reflux, often referred to as GERD occurs when acid from the stomach backs up into the esophagus. Over time, reflux progressively overwhelms the body’s natural anti-reflux defenses, inflaming the relevant mechanisms until they no longer function at all, leading to constant, chronic reflux. Truly, a vicious cycle. Laryngopharyngeal reflux (LPR) is similar to another condition -- GERD-- that results from the contents of the stomach backing up (reflux). But the symptoms of LPR are often different than those. Diagnosed with Silent Reflux, prescribed Nexium. Some questions. Follow Posted 3 years ago, 11 users are following. This discussion has been locked due to a period of inactivity. Start a new discussion. walterw. Hi, My ENT put a scope down my throat and diagnosed me with a proabably new and not very severe case of silent reflux. My symptoms are a slight burning in the throat and mucus. There is a lack of consistent guidelines and consensus for the diagnosis of laryngopharyngeal reflux (LPR). A therapeutic trial with a proton pump inhibitor (PPI) has been suggested to identify patients with LPR. Your doctor has diagnosed you as having Laryngopharyngeal Reflux Disease or LPR. This condition develops when stomach acid travels up into your throat. Although you may experience heartburn or indigestion , many of our patients do not have these complaints.