Omeprazole (Prilosec) is an inexpensive drug used to treat certain conditions where there is too much acid in the stomach like ulcers and gastroesophageal reflux disease. It is more popular than comparable drugs. Compare prices, print coupons and get savings tips for Zantac (Ranitidine) and other Heartburn, Gastric Ulcer, GERD, and Duodenal Ulcer drugs at CVS, Walgreens, and other pharmacies. Prices start at $6.60 Heartburn is different for everyone & there are a variety of OTC heartburn treatment options. Compare heartburn medications to find out which one is right for you. Zantac (ranitidine hydrochloride) is a H2 (histamine-2) receptor blocker used for treating and preventing ulcers in the duodenum and stomach. Zantac is also used for treating Called proton pump inhibitors (PPIs), this group of drugs includes Prilosec, Nexium and Prevacid. They work by lowering the amount of acid produced by the stomach. 9 Answers (question resolved) - Posted in: prevacid, prilosec, pain, gerd - Answer: Each of these meds work in different ways. I use nexium and it. Which is better for acid reflux - Prevacid or Prilosec? Posted 15 Feb 2010 • 9 answers. I have been told I have a hiatus hernia and have been experiencing pain in my back and my chest. Antacids, H2 blockers, and surgery are a few of the alternatives to Zantac. This eMedTV Web segment takes a look at when these options may be recommended and lists specific examples of drugs that may work as a substitute. Zantac vs Prilosec. Over-the-counter drugs have made self-medication easy and quick for most people, not to mention that they save a lot on consultation fees. Prilosec and Diarrhea -- How Common Is It? Before medicines are approved, they must go through several clinical studies in which thousands of people are given a particular medicine and are then compared to a group of people not given the medicine.