Those with liver disease must be aware that the three most common pain relievers could be hazardous to a compromised liver – even at a reasonable dosage. Oxycontin is broken down in the liver so yes it does affect the liver, and in large doses over a prolonged period of time, it will cause damage. Prolonged alcohol abuse can cause serious damage to the liver, and can also lead to lasting health problems like alcoholic cirrhosis and fatty liver disease. GOLD CROSS CODEINE LINCTUS. Codeine phosphate hemihydrate. Consumer Medicine Information. WHAT IS THIS LEAFLET. This leaflet answers some common questions about Gold Cross Codeine Linctus. Doctors give trusted answers on uses, effects, side-effects, and cautions: Dr. Fung on benadryl and liver damage: There is a caution warning for this medication with any liver impairment. Discuss this with your liver specialist. Learn how to keep your liver as safe as possible when choosing a pain reliever with chronic liver disease. Doctors give trusted answers on uses, effects, side-effects, and cautions: Dr. Kamyar on ambien liver damage: Combination of Acetaminophen with Codeine can lead to hepatotoxicity or liver damage. APO-Paracetamol/Codeine 500/30 Tablets - Consumer Medicines Information leaflets of prescription and over-the-counter medicines So, you have been diagnosed with Fatty Liver Disease, and now you’re full of questions and wondering where to go from here. Perhaps the very first thing you should do, before anything else, is to gain a clear understanding of exactly what this disease is. Ask questions and get answers about Liver. Our support group helps people share their own experience. 204 questions, 319 members.