Best Answer: I take Abilify 10 mg for schizophrenia. At first I took it all in the morning. Then I began to be really paranoid at night that someone would break in the house and kill me. if your pdoc believes the Abilify is sedating or will make you drowsy, ask her or him when you can take it so that you won't wind up drowsy in the morning or afternoon. As with any medicine, it's important to take ABILIFY (aripiprazole) exactly as directed, for as long as your doctor prescribes it. Here is some information that can help. There is need for individualization of drug therapy, ifaripiprazole isn't good, the person may try quetiapine. I took Abilify (if for two days only) while I was on Luvox, an SSRI similar to Zoloft. The thing is, though, your doctor is the one who can deterime if it is safe for you to take both Zoloft and Abilify, and decide if you need that to be added. You should take Abilify at bed time because one of the most common side effects of the drug is that it makes you sleepy. So it seems natural to take something that makes you sleepy at bed time. Take Abilify exactly as prescribed by your doctor. Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not take this medicine in larger or smaller amounts or for longer than recommended. Take the dose of Abilify when you remember, but skip the missed dose if it it’s almost time for your next dose. You should never take extra doses of the medication to make up for missed doses. You should never take extra doses of the medication to make up for missed doses. How to use Abilify. Read the Medication Guide and, if available, the Patient Information Leaflet provided by your pharmacist before you start taking aripiprazole and each time you get a refill. Anyone else on abilify? Do you take it in the morning or at night? Any reason you prefer one or the other? I asked my psychiatrist and she said that most people take it in the morning, but if I have any drowsiness I can try taking it at night.