Many of the health issues that come with gabapentin abuse will resolve when you clear your body of the substance and stay drug-free. Professional rehabilitation can be an important stepping stone to a healthy and substance-free future. Based on this half-life estimation, gabapentin can stay in the system for anywhere from 1.15 to 1.60 hours after someone takes their last dose. For the majority of people, gabapentin wouldn’t be in their system two days after the last dose. How long can Gabapentin be detected in your urine, blood, saliva? Gabapentin, also known as Neurontin, is a drug that acts on the central nervous system. This article tries to give you an answer to the question ‘how long does Gabapentin stay in your system.’ Gabapentin is neither a controlled substance nor a narcotic. 50% of gabapentin is eliminated from the system in 5 to 7 hours and can remain in the body up to 1.15 to 1.60 days after the final dose, which means that the drug is entirely excreted from the system after approximately two days after ingestion. You can expect Gabapentin to remain in your hair for a lot longer, maybe even weeks. However, most drug tests for Gabapentin will likely be performed on urine. However, most drug tests for Gabapentin will likely be performed on urine. rheumatoid arthritis, pain, back pain, sciatica, gabapentin, bones, bone, mri, stenosis Details: I have had 2 back surgeries including a double-fusion using my own bone. You may be wondering how long can a dog take gabapentin, since epilepsy can be a life-long condition. With epilepsy in dogs, gabapentin is taken as long as the pup needs it, which can be months or even years. After taking gabapentin for my nerve pain (sciatica), the pain on my leg has stopped completely.