Bupropion hydrochloride tablets (immediate release): 75 mg, 100 mg Bupropion hydrochloride tablets (sustained release): 100 mg, 150 mg, 200 mg Bupropion hydrochloride tablets (extended release): 150 mg, 300 mg Bupropion hydrobromide tablets (extended release): 174 mg, 348 mg, 522 mg Bupropion is an According to the FDA Budeprion XL 300 mg (manufactured by Impax Laboratories) is NOT therapeutically equivalent to Wellbutrin XL 300 mg 4. Bupropion was first synthesized by Burroughs Research in 1966, and patented by Burroughs-Wellcome (later Glaxo-Wellcome) in 1974. Pictures of Wellbutrin (Bupropion Hcl), drug imprint information, side effects for the patient. Bupropion, sold under the brand names Wellbutrin and Zyban among others, is a medication primarily used to treat major depressive disorder and to support stopping smoking. It is an effective antidepressant on its own, but is also used as an add-on medication in cases of incomplete response to first-line SSRI antidepressants. WELLBUTRIN XL®, the only extended-release bupropion with more than 15 years of experience in Major Depressive Disorder (MDD) and more than 10 years of experience in Seasonal Affective Disorder (SAD). DESCRIPTION. WELLBUTRIN (bupropion hydrochloride), an antidepressant of the aminoketone class, is chemically unrelated to tricyclic, tetracyclic, selective serotonin re-uptake inhibitor, or other known antidepressant agents. page 2 of 14 digoxin tab 125 mcg (0.125 mg), 250 mcg (0.25 mg) (Lanoxin) disopyramide phosphate cap 100 mg, 150 mg (Norpace) dofetilide cap 125 mcg (0.125 mg), 250 mcg Initially, 150 mg PO once daily in the morning. After no less than 4 days, titrate to the usual target dose of 300 mg PO once daily in the morning based upon patient response and tolerance. In clinical trials with Bupropion HCl immediate-release, 10% of patients and volunteers discontinued due to an adverse reaction. Reactions resulting in discontinuation (in addition to those listed above for the sustained-release formulation) included vomiting, seizures, and sleep disturbances. I've been taking Bupropion XL for years. Due to recent changes in my insurance, I've had to switch pharmacies. My new pharmacist refilled my prescription with Bupropion HCL XL as opposed to the Bupropion XL I'm used to.