For the treatment of hypercholesterolemia, including hyperlipidemia, hyperlipoproteinemia, or hypertriglyceridemia, as an adjunct to dietary control; and for reduction in cardiovascular mortality, including myocardial infarction prophylaxis and stroke prophylaxis. Table of Substrates, Inhibitors and Inducers (including: CYP Enzymes, Clinical index drugs, transporters, and examples of clinical substrates, inhibitors, and inducers). Diflucan ® (fluconazole), the first of a new subclass of synthetic triazole antifungal agents, is available as tablets for oral administration, as a powder for oral suspension. Usual starting dose is ezetimibe 10 mg/simvastatin 10 mg or ezetimibe 10 mg/simvastatin 20 mg PO once daily in the evening. May initiate at ezetimibe 10 mg/simvastatin 40 mg PO once daily in the evening for patients requiring a larger reduction in LDL-C (greater than 55%). (Detail-Document 150400: Page 4 of 4) Original publication date April 1999 CYP2C8 -----Substrates----- -----Inhibitors----- --Inducers-- In normal volunteers, Fluconazole is cleared primarily by renal excretion, with approximately 80% of the administered dose appearing in the urine as unchanged drug. ArcMesa Educators has provided more than 400,000 credit hours and awarded 210,000 certificates to physicians and physician assistants, nurses, radiologic technologists, dentists and dental hygienists, dieticians, funeral directors and many others seeking credits for license renewal. Fluconazole oral tablet can interact with other medications, vitamins, or herbs you may be taking. An interaction is when a substance changes the way a drug works. Simvastatin, marketed under the trade name Zocor among others, is a lipid-lowering medication. It is used along with exercise, diet, and weight loss to decrease elevated lipid levels. It is also used to decrease the risk of heart problems in those at high risk. It is taken by mouth. Benzocaine sprays - FDA continues to receive reports of serious and potentially fatal adverse effects with the use of benzocaine sprays for medical procedures Benzocaine gels and.