Verapamil ER is an extended-release form of verapamil that is used to treat high blood pressure. The prescribing information does not specifically list enlarged aorta as a possible long-term side. Dosage warning: Your doctor will determine the right dose for you and may increase it gradually. Verapamil takes a long time to break down in your body, and you may not see an effect right away. How to use Verapamil HCL. Take this medication by mouth with or without food as directed by your doctor, usually 3 or 4 times daily. The dosage is based on your medical condition and response to. These brands come in slightly higher doses with 160 mg, 180 mg or 240 mg, but is released more slowly so that you only need to take one capsule each day. Tarka is in a category of its own because it contains both verapamil (180 mg or 240 mg) with trandolapril (2 mg or 4 mg) in one controlled release capsule that can be taken once per day. For oral dosage form (extended-release tablets, 24 hr): Adults—At first, 180 milligrams (mg) once daily at bedtime. Your doctor may adjust your dose if needed. Medscape - Hypertension, angina, atrial fibrillation-specific dosing for Calan SR, Isoptin SR, (verapamil), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost information. Detailed Verapamil dosage information for adults, the elderly and children. Includes dosages for Hypertension, Angina Pectoris, Arrhythmias and more; plus renal, liver and dialysis adjustments. Verapamil is a calcium channel blocker. It works by relaxing the muscles of your heart and blood vessels. Verapamil is used to treat hypertension (high blood pressure), angina (chest pain), and certain heart rhythm disorders. Verapamil, sold under various trade names, is a medication used for the treatment of high blood pressure, angina (chest pain from not enough blood flow to the heart), and supraventricular tachycardia.