500 mg PO on first day of therapy, followed by 250 mg PO once daily on days 2 to 5. Guidelines recommend azithromycin as a monotherapy option in previously healthy outpatients with no risk factors for drug-resistant S. pneumoniae and without therapy in the preceding 3 months. For the Consumer. Applies to mefloquine: oral tablet. Along with its needed effects, mefloquine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. SIDE EFFECTS Clinical Trials Experience. Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice. Side Effects. See also Warning section. Diarrhea, dizziness, drowsiness, hair loss, blurred/double vision, change in menstrual periods, ringing in the ears, shakiness. Components Description Dose Sulfadoxine-pyrimethamine (SP) (Fansidar) This fixed-dose combination has been used for many years, causes few adverse effects, is cheap and effective in a single dose, thus decreasing problems associated with adherence and compliance. Mefloquine, sold under the brand names Lariam among others, is a medication used to prevent or treat malaria. When used for prevention it is typically started before potential exposure and continued for several weeks after potential exposure. It can be used to treat mild or moderate malaria but is not recommended for severe malaria. It is taken. LARIAM® (mefloquine hydrochloride) Tablets. DESCRIPTION. Lariam (mefloquine hydrochloride) is an antimalarial agent available as 250-mg tablets of mefloquine hydrochloride (equivalent to 228.0 mg of the free base) for oral administration. Psychiatric Side Effects. According to the current U.S. mefloquine package insert, 70 psychiatric symptoms associated with prophylactic mefloquine use include abnormal dreams, anxiety, paranoia, agitation, confusion, memory impairment, and hallucinations. Find patient medical information for Depakote Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Mefloquine Hydrochloride Tablets, USP are an antimalarial agent available as 250-mg tablets of Mefloquine hydrochloride (equivalent to 228.0 mg of the free base) for oral administration.