This is a ten-week, double-blind, placebo-controlled study designed to evaluate the tolerability, dosing and efficacy of Wellbutrin XL in outpatients who meet Diagnostic and Statistical Manual-IV criteria for early onset, primary type dysthymic disorder (low-grade chronic depression). 1. J Clin Psychopharmacol. 2001 Jun;21(3):325-9. Bupropion sustained-release for the treatment of dysthymic disorder: an open-label study. Hellerstein DJ(1), Batchelder S, Kreditor D, Fedak M. 178 Wellbutrin xl users have rated its effectiveness for Dysthymic disorder. Overall ratings: 3.3/5 Long term ratings: 3.4/5. This is a reivew of how effective Wellbutrin xl (bupropion hydrochloride) is for Dysthymic disorder and for what kind of people. Wellbutrin XL for Dysthymic Disorder. … Hamilton Depression Rating Scale, 24 Items … Cornell Dysthymia Rating Scale (CDRS) … Cornell Dysthymia Rating Scale (CDRS) 20 … The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Overview. This is a ten-week, double-blind study of Wellbutrin XL in outpatients with dysthymic disorder, a form of low-grade chronic depression. Bupropion sustained-release for the treatment of dysthymic disorder: an open-label study by Hellerstein DJ, Batchelder S, Kreditor D, Fedak M. Department of Psychiatry, Wellbutrin XL and SR benefits, side effects – Wellbutrin XL and SR side effects and use for depression, benefits – Interactions with nutritional supplements and proper dosage by Ray Sahelian, M.D…. I am 18 and I was diagnosed with dysthymia when I was 14. I noticed signs of depression from the age of 10 years old. My sophomore year of highschool, the doctor prescribed me different medz over a short period of time. User Reviews for Bupropion to treat Persistent Depressive Disorder Also known as: Aplenzin, Buproban, Forfivo XL, Wellbutrin SR, Wellbutrin XL, Zyban, Zyban Advantage Pack The following information is NOT intended to endorse drugs or recommend therapy.