Trazodone helps take the edge off of some wicked withdrawal symptoms that are often reported such as inability to fall asleep, or broken sleep throughout the night. Effective : It’s no secret that Trazodone is effective for treating insomnia, which is why it has gained popularity as a sleep-inducing agent. Trazodone is especially effective as a sleep-aid for people with insomnia and sleep disorders due to depression. Conversely, some antidepressant drugs can cause sleep deprivation, trazodone can be used to treat insomnia caused by other antidepressants. It may also be prescribed as a sleep aid even for people without depression. Detailed Trazodone dosage information for adults. Includes dosages for Depression and Depression; plus renal, liver and dialysis adjustments. A trazodone dosage begins at 50 mg, then includes 100, 150 and 300 mg. In many patients, the tablets can be divided to get a more specific, correct dosage. In many patients, the tablets can be divided to get a more specific, correct dosage. A: Trazodone (Desyrel) is an antidepressant commonly used to treat depression and sleep disorders. Some of the common side effects associated with trazodone include drowsiness, headache. Trazodone Trazodone HCl (generic Desyrel) is a modified cyclic antidepressant used as a treatment for depression. It may also be used for relief of an anxiety disorder (e.g., tension, sleeplessness), chronic pain or to treat other conditions as determined by your doctor. Dosage for trazodone depends on what conditions the patient is being treated. Click for more about trazodone during pregnancy and while breastfeeding. Click for more about trazodone during pregnancy and while breastfeeding. The trazodone max dose for sleep can vary depending on the individual, but the general max dose of trazodone in a day is 300 mg. With that being said, when it comes to trazodone and insomnia, lower doses tend to be more effective, and higher doses may not be effective for insomnia or could even cause more insomnia.