Find patient medical information for Misoprostol Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Misoprostol reduces stomach acid and helps protect the stomach from damage that can be caused by taking a nonsteroidal anti-inflammatory drug (NSAID) such as aspirin, ibuprofen (Advil, Motrin), naproxen , celecoxib, diclofenac, indomethacin, meloxicam, and others. Diclofenac-misoprostol oral tablet is available as a brand-name drug and a generic drug. Brand name: Arthrotec. Diclofenac-misoprostol comes only as a delayed-release oral tablet. DESCRIPTION. ARTHROTEC (diclofenac sodium/misoprostol) is a combination product containing diclofenac sodium, a nonsteroidal anti-inflammatory drug (NSAID) with analgesic properties, and misoprostol, a gastrointestinal (GI) mucosal protective prostaglandin E 1 analog. Warning This medicine may cause birth defects, loss of the unborn baby, or premature birth if you take it while you are pregnant. It may also cause the uterus to tear (rupture). Adverse Effects Potential Problems with Misoprostol. Misoprostol, like the vast majority of drugs, has potential adverse effects. The Summary of Product Characteristics (SPC) for Cytotec lists adverse effects and potential dangers of the drug. Misoprostol, like the vast majority of drugs, has potential adverse effects. The Summary of Product Characteristics (SPC) for Cytotec lists the potential problems - link here for more details, and for ways of avoiding complications. warning. cytotec (misoprostol) administration to women who are pregnant can cause birth defects, abortion, premature birth or uterine rupture. uterine rupture has been reported when cytotec was administered in pregnant women to induce labor or to induce abortion. Cytotec (Misoprostol) is a drug that was originally developed as a medicinal product to protect the cavity of the stomach and duodenum from excessively rapid reabsorption of the mucous protective layer. The Abortion Pill: Medical Abortion with Mifepristone and Misoprostol. What is the Medical Abortion? Medical Abortion (brand name Mifeprex) is a form of early abortion caused by the combination of two medications, mifepristone and misoprostol that is an option for women who are 8 weeks pregnant.