According to the International Headache Society, around 30 percent of people with an underactive thyroid gland (hypothyroidism) will have a history of headaches. Summary. Headaches is found among people who take Synthroid, especially for people who are female, 60+ old , have been taking the drug for 1 month, also take medication Nexium, and have High blood pressure. Migraine is a primary headache and is not *caused* by another disease or disorder. Thyroid disease however is a condition that is a frequent Migraine trigger for those patients unlucky enough to have both conditions — called a co-morbidity. On the other hand, migraine headaches are one of the favorite symptoms to treat for doctors that treat Wilson’s Temperature Syndrome because of how debilitating the condition is and because of how well it responds to treatment. Yes, Synthroid can cause headaches, but you must not stop the medication without consulting your doctor. Thyroid disorder itself can be associated with headaches and migraines. You can ask your doctor for a prescription medication that can prevent migraines. Headaches can be disabling and occur at the most unexpected times, leading to impairment in productivity and function in the workplace, as well as other possible complications. There are different types of headaches that a person can experience. A migraine is, by far, the most unpleasant type of a headache. Migraines affect approximately 14.7% of the worldwide population, and as much as 2% of. I've been getting these headaches at the base of my skull the last week or so. I've been on Synthroid for 6 weeks now. I've read some websites that some people get headaches for a while when they first start on Synthroid. Migraine & Headaches. News. How Does Migraine Affect Your Body? Can You Blame Your Headaches on Your Thyroid? People with migraines had 40 percent higher risk of thyroid problems, study suggests. Can Levothyroxine cause severe migraine attack Can Levothyroxine cause severe migraine attack Hi -I've been on it 7 days and my chronic headache has been significantly worse since day 2. I tried Levo 2yrs ago when I was migraine preventTives and even then I had a bad headache for a week. Can Synthroid cause headaches? Asked 15 Sep 2013 by vernonsavoie Updated 15 September 2013 Topics headache.