Digoxin is a cardiac glycoside. Digoxin inhibits the sodium potassium adenosine triphosphatase (ATPase) pump, thereby increasing intracellular calcium and enhancing cardiac contractility. Signs and Symptoms of Digoxin Exposure: Acute digoxin ingestion may produce the following signs and symptoms: nausea, vomiting, headache, lethargy, drowsiness, confusion, slowed pulse, varying degrees of heart block, and heart arrhythmias. Coma, respiratory failure, and heart failure may also occur. Lists the various brand names available for medicines containing digoxin. Find information on digoxin use, treatment, drug class and molecular formula. Digoxin, sold under the brand name Lanoxin among others, is a medication used to treat various heart conditions. Most frequently it is used for atrial fibrillation, atrial flutter, and heart failure. Digoxin is taken by mouth or by injection into a vein. Preparation. 1,4-Dioxin can be prepared by cycloaddition, namely by the Diels–Alder reaction of furan and maleic anhydride. The adduct formed has a carbon-carbon double bond, which is converted to an epoxide. Digitoxin is a lipid soluble cardiac glycoside that inhibits the plasma membrane sodium potassium ATPase, leading to increased intracellular sodium and calcium levels and decreased intracellular potassium levels. Specifies the medication digoxin (Lanoxin), a drug used to treat congestive heart failure and the associated symptoms of shortness of breath when lying flat, wheezing, and ankle swelling. This page was last edited on 11 March 2019, at 21:38. All structured data from the main, property and lexeme namespaces is available under the Creative Commons CC0 License; text in the other namespaces is available under the Creative Commons Attribution-ShareAlike License; additional terms may apply. Digoxin. In some countries, this medicine may only be approved for veterinary use. In the US, Digoxin (digoxin systemic) is a member of the following drug classes: group V antiarrhythmics, inotropic agents and is used to treat Atrial Fibrillation and Heart Failure. DESCRIPTION Digoxin is one of the cardiac (or digitalis) glycosides, a closely related group of drugs having in common specific effects on the myocardium.