Acetaminophen is an analgesic used to temporarily relieve minor aches and pains. Learn about side effects, drug interactions, dosages, warnings, and more. Acetaminophen — better known by the brand name Tylenol — is an over-the-counter pain reliever. It can be used to help with mild to moderate headaches, muscle aches, backaches, sore throats and. Pictures of Tylenol (Acetaminophen), drug imprint information, side effects for the patient. Learn about the potential side effects of Tylenol Extra Strength (acetaminophen). Includes common and rare side effects information for consumers and healthcare professionals. Tylenol is associated with serious complications, including liver damage and rare but dangerous skin reactions. It is the leading cause of acute liver failure in the U.S., and the drug in some cases led to fatalities. Generic Name: acetaminophen and diphenhydramine (a SEET a MIN oh fen and DYE fen HYE dra meen) Brand Name: Aceta-Gesic, Coricidin Night Time Cold Relief, Excedrin PM, Headache Relief PM, Legatrin PM, Mapap PM, Midol PM, Night Time Pain, Pain Relief PM Extra Strength, Percogesic Extra Strength, Tylenol Cold Relief Nighttime, Tylenol PM, Tylenol. Acetaminophen is a drug used to relieve pain and reduce fever. Most people don't experience side effects with this drug when it is used appropriately. Common side effects are nausea, rash, and headache. Adverse and serious side effects are kidney damage, anemia, anyphylaxis, and liver failure. Acetaminophen overdose or poisoning can occur if very large amounts of Extra Strength Tylenol are taken. Within hours of ingestion, some may experience symptoms of gastroenteritis such as abdominal cramping and bloating, low-grade fever or diarrhea. Acetaminophen is the generic name for Tylenol, a pain reliever and fever reducer. It's one of the most widely used pain medications in the world. TYLENOL® Extra Strength Coated Tablets for Adults should be used to temporarily reduce fever and relieve minor aches and pains. Each extra-strength pain relief coated tablet contains 500 milligrams of acetaminophen and can be a safe and effective post-surgery pain relief option when used as directed.