Nizoral Anti-Dandruff Shampoo is a powerful formula that controls flaking, scaling and itching. It combines the effectiveness of ketoconazole, a proven dandruff-fighting ingredient, with salon-tested gentleness. NIZORAL ® (ketoconazole) 2% Shampoo is a red-orange liquid for topical application, containing the broad spectrum synthetic antifungal agent ketoconazole in a concentration of 2% in an aqueous suspension. Prescription ketoconazole comes as a cream and a shampoo to apply to the skin. Over-the-counter ketoconazole comes as a shampoo to apply to the scalp. Nizoral® (ketoconazole) 2% Shampoo. DESCRIPTION. NIZORAL® (ketoconazole) 2% Shampoo is a red-orange liquid for topical application, containing the broad spectrum synthetic antifungal agent ketoconazole in a concentration of 2% in an aqueous suspension. Learn about NIZORAL®, an anti-dandruff shampoo treatment that helps to control scalp flaking, scaling, and itching when used between regular washings. Nizoral shampoo is commonly used to treat dandruff and other skin infections. However, recently, there are evidences from various studies indicating that Nizoral shampoo can actually stop hair loss and even promote hair regrowth. NIZORAL® A-D Ketoconazole 1% Shampoo, when used twice a week, helps to control scaling, itching, flaking scap to reveal dandruff-free, healthy hair. I tried Nizoral OTC (1%) for a while. It was a little harsh on my scalp. The hair around my crown actually changed color and thinned out a little bit as a result. You’re probably familiar with ketoconazole shampoo, though you might not know it. Ketoconazole shampoo is commonly used to fight and prevent seborrheic dermatitis (dandruff) and other types of skin conditions caused by fungal infections. Adults and children 12 years and over: wet hair thoroughly apply shampoo, generously lather, rinse thoroughly. Repeat use every 3-4 days for up to 8 weeks or as directed by a doctor.