Betaloc CR tablets 95mg contain metoprolol, a beta-blocker, which slows the heart rate, dilates (widens) blood vessels and lowers blood pressure and is used to treat variety of conditions of the cardiovascular system, including high blood pressure, angina, heart failure and to prevent heart attack. Hypertension. Metoprolol Succinate extended-release tablets are indicated for the treatment of hypertension, to lower blood pressure. Lowering blood pressure lowers the risk of fatal and non-fatal cardiovascular events, primarily strokes and myocardial infarctions. Metoprolol Succinate ER is a prescription medication dispensed in a 25 mg tablet form for oral ingestion. Produced by the pharmaceutical company AstraZeneca under the brand name of Toprol XL, Metoprolol Succinate ER was approved by the FDA in 2001. Pharmacodynamic Effects, Safety and Tolerability of Cilobradine, Compared to Metoprolol Succinate and Placebo in Healthy Volunteers Metoprolol Succinate Pharmacokinetics Absorption Bioavailability. Metoprolol tartrate is rapidly and almost completely absorbed from the GI tract. 109 After an oral dose (as conventional tablets), about 50% of the drug undergoes first-pass metabolism in the liver. 109 DESCRIPTION. TOPROL-XL, metoprolol succinate, is a beta 1-selective (cardioselective) adrenoceptor blocking agent, for oral administration, available as extended-release tablets. Abrupt discontinuation of any beta-adrenergic-blocking agent, including metoprolol, can result in the development of myocardial ischemia, myocardial infarction, ventricular arrhythmias, or severe hypertension, particularly in patients with preexisting cardiac disease. Find patient medical information for Metoprolol Succinate Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Drug Information on Lopressor, Metoprolol Succinate ER, Metoprolol Tartrate (metoprolol) includes drug pictures, side effects, drug interactions, directions for use, symptoms of overdose, and what to avoid. Medical uses. Metoprolol is used for a number of conditions, including hypertension, angina, acute myocardial infarction, supraventricular tachycardia, ventricular tachycardia, congestive heart failure, and prevention of migraine headaches.