Depot medroxyprogesterone acetate (DMPA) is an injectable contraceptive that has been used by approximately 1 in 5 adolescents and adult women in the United States who have had sex 1.Depot medroxyprogesterone acetate is a highly effective contraceptive that affords privacy (similar to an intrauterine system) and has a convenient dose schedule of four times per year, making it appealing to many. Medroxyprogesterone acetate is used for the treatment of hot flushes caused by long-term androgen suppression in men, but it is not licensed for this indication. Contra-indications. Acute porphyrias; current breast cancer (unless progestogens are being used in the management of this condition) With oral use. history of thromboembolism; undiagnosed vaginal bleeding. Cautions. Cardiac. Medroxyprogesterone belongs to a group of medicines called progestogens, which are female hormones. When it is prescribed to help problems such as heavy, painful, irregular or missed periods, it works by replacing or supplementing the naturally produced female sex hormone called progesterone. Medroxyprogesterone is also used for endometriosis. Medroxyprogesterone acetate HCPCS Modifier 1: HCPCS Pricing indicator 51 - Drugs Multiple pricing indicator A - Not applicable as HCPCS priced under one methodology Coverage code C - Carrier judgment: BETOS 2 code O1E - Other drugs: HCPCS Action code N - No maintenance for this code: Type of service 1 - Medical care: Effective date Effective Jan 01, 2013: Date added Added Jan 01, 2013: HCPCS. Medroxyprogesterone acetate 400 mg; 30: tablet (POM) £58.67 Part VIIIA Category C: £58.67: Suspension for injection All products. Depo-Provera 150mg/1ml suspension for injection pre-filled syringes (Pfizer Ltd) Active ingredients. Provera tablets contain the active ingredient medroxyprogesterone acetate, which is a synthetic form of the naturally occurring female sex hormone, progesterone. Treating period problems. A woman. Li CI, Beaber EF, Tang, MCT et al. Effect of Depo-Medroxyprogesterone Acetate on Breast Cancer Risk among Women 20 to 44 years of Age. Cancer Research 2012;72:2028–2035. Paul C, Skegg DCG, Spears. Medroxyprogesterone acetate is administered every 3 months which in turn prevents ovulation and follicular maturation in endometrial thinning producing a contraceptive effect. Request for Table of. Medroxyprogesterone injection is a long-acting birth control method. You might not become pregnant for some time after you receive your last injection. Talk to your doctor about the effects of using this medication if you plan to become pregnant in the near future. Medroxyprogesterone injection may cause other side effects. Call your doctor if you have any unusual problems while receiving this. Medroxyprogesterone is usually given for only a few days in a row each month. Have regular physical exams and self-examine your breasts for lumps on a monthly basis while using this medicine. If you need major surgery or will be on long-term bed rest, you may need to stop using medroxyprogesterone for a short time.