Treatment of Active Duodenal Ulcer. Lansoprazole delayed-release capsules are indicated in adults for short-term treatment (for four weeks) for healing and symptom relief of active duodenal ulcer [see Clinical Studies (14.1)]. LeAnn W. O’Neill, PharmD Clinical Pharmacist Barney’s LTC Pharmacy Augusta, Georgia. Benjamin L. Culpepper, PharmD PGY-2 Community/Academia Pharmacy Resident Discover the problems that may arise with chronic use of proton pump inhibitors and other heartburn medications Information on lansoprazole (Heartburn Relief 24 Hour, Heartburn Treatment 24 Hour, Prevacid 24), a drug used to treat ulcers of the stomach and duodenum, gastroesophageal reflux disease (GERD) and Zollinger-Ellison Syndrome. Side effects, drug interactions, dosing, storage, and pregnancy and breastfeeding safety is included. Lansoprazole is used to treat stomach and intestinal ulcers, erosive esophagitis and Zollinger-Ellison syndrome. Learn about side effects, interactions and indications. For the short-term treatment of frequent dyspepsia or pyrosis (heartburn) that occurs 2 or more times per week. Proton-pump inhibitors relieve acid reflux, but people who take them long-term may be more susceptible to certain bacterial infections, pneumonia, and bone… Learn about Prevacid (Lansoprazole) may treat, uses, dosage, side effects, drug interactions, warnings, patient labeling, reviews, and related medications. Zantac can be accompanied by a number of serious, but rare, side effects. Because of their rarity, they are not well studied and it is unclear whether they occur with long-term or short-term use. Prevacid (lansoprazole) is a proton pump inhibitor (PPI) used to treat and prevent stomach and intestinal ulcers, erosive esophagitis (damage to the esophagus from stomach acid), and other conditions involving excessive stomach acid such as Zollinger-Ellison syndrome.