Chronic use of ibuprofen can result in gastritis, ulceration with or without GI perforation, and/or GI bleeding, which can occur at any time, often without preceding symptoms. When you hear the word “overdose,” images of hard drugs or powerful prescription medications probably come to mind. And chances are, you’ve never even thought about an ibuprofen overdose, but it turns out that not only can you have too much of this relatively mild pain reliever, it can put your health in peril. Something else to be aware of as far as ibuprofen side effects is that it should *never* be taken by women in late pregnancy. It is known to cause heart defects in newborns that can be very dangerous. Ibuprofen Tablets, USP, a nonsteroidal anti-inflammatory drug (NSAID), is available in 400 mg, 600 mg, and 800 mg tablets for oral administration. This site uses cookies. By continuing to browse this site you are agreeing to our use of cookies. Ibuprofen tablets contain the active ingredient Ibuprofen, which is (±) -2 - ( p - isobutylphenyl) propionic acid. Ibuprofen is a white powder with a melting point of 74-77° C and is very slightly soluble in water( 1 mg/mL) and readily soluble in organic solvents such as ethanol and acetone. Click one of the letters above to advance the page to terms beginning with that letter. Ibuprofen is a commonly used nonsteroidal antiinflammatory (NSAID) drug which is available both by prescription and over-the-counter. Ibuprofen is considered to be among the safest NSAIDs and is generally well tolerated but can, nevertheless, rarely cause clinically apparent and serious acute liver injury. DESCRIPTION. DUEXIS (ibuprofen and famotidine) is supplied as a tablet for oral administration which combines the nonsteroidal anti-inflammatory drug, ibuprofen, and the histamine H2-receptor antagonist, famotidine. A recent Reuters' article opened with the following stunning sentence: Long-term high-dose use of painkillers such as ibuprofen or diclofenac is 'equally hazardous' in terms of heart attack risk as use of the drug Vioxx, which was withdrawn due to its potential dangers, researchers said. .