Interactions. See also How to Use section. Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug. CRESTOR ® (rosuvastatin calcium) may cause serious side effects, including: Muscle pain, tenderness and weakness (myopathy). Muscle problems, including muscle breakdown, can be serious in some people and rarely cause kidney damage that can lead to death. Crestor (rosuvastatin) is used to treat high cholesterol and high triglycerides in the blood. Includes Crestor side effects, interactions and indications. If your doctor has directed you to use this medication, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Crestor (Rosuvastatin) is a statin drug prescribed by physicians that studies reveal helps to lower a person’s cholesterol levels some 45 to 65 percent. Drug Information on Crestor (rosuvastatin) includes drug pictures, side effects, drug interactions, directions for use, symptoms of overdose, and what to avoid. Our Crestor Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication. This is not a complete list of side effects and others may occur. Along with its needed effects, rosuvastatin (the active ingredient contained in Crestor) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Consumer information about the medication ROSUVASTATIN - ORAL (Crestor), includes side effects, drug interactions, recommended dosages, and storage information. Read more about the prescription drug ROSUVASTATIN - ORAL. This allows your pharmacist to keep a complete record of all your prescription drugs and to advise you about drug interactions and side effects. Tell your health-care provider about any negative.