It works by helping change certain chemicals in the brain, which professionals refer to as “neurotransmitters.” It is not yet well-understood why changing these neurochemicals results in. People who abuse citalopram or take the drug long-term are at risk for developing respiratory infections. Learn more about the long-term effects of citalopram. Wellbutrin XL - How long does it usually take to feel any effects? Asked 27 Mar 2014 by joelyn28 Updated 4 September 2015 Topics prozac, wellbutrin xl, bupropion Wellbutrin is available as a standard pill of 75 milligrams (mg) and 100 mg, as a sustained-release pill (100 mg), and as a long-acting extended-release tablet (150 and 300 mg). It usually takes four weeks (and maybe even longer) to feel the full, beneficial effects of Wellbutrin. Try not to be discouraged if the drug does not work right away for you. Can anyone answer these questions for me or help me find someone who can. I started 150mg 1a day a week ago sence then im eating everything I can get my hands on and that worries me. DESCRIPTION. WELLBUTRIN (bupropion hydrochloride), an antidepressant of the aminoketone class, is chemically unrelated to tricyclic, tetracyclic, selective serotonin re-uptake inhibitor, or other known antidepressant agents. Dizziness is one of Wellbutrin’s most well-known side effects, one with which I’ve become intimately familiar. Since I know I need an antidepressant right now and refuse to take any with sexual side effects, I’ve become experienced in managing Wellbutrin side effects. My experience is very similar. I was 125 lbs when I started taking Paxil for anxiety and gained about 40lbs over the course of 2 years. I started on Wellbutrin at the suggestion of my Dr. when I advised that I no longer wanted to take it due to the horrible weight gain. close What To Expect. Seeking addiction treatment can feel overwhelming. We know the struggle, which is why we're uniquely qualified to help. Your call is confidential, and there's no pressure to commit to treatment until you're ready.