How Do New Blood Thinners Compare to Warfarin?. and it affects how well the drug works. You need to be consistent in how much you eat. It's not that you can't eat salads, Lindsay says. If. In a non-inferiority trial, researchers set a level at which they would decide that the new drug might be inferior to the old drug. In this case, the researchers decided that they needed to be at least 97.5% confident that dabigatran would not increase the risk of stroke or systemic embolism by 1.46 times or greater compared with warfarin. Warfarin drug interactions (in more detail) Further information Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use warfarin only for the indication prescribed. Newer medications are now available as alternatives to warfarin. Some of these drugs are oral medications. Others you inject under your skin. The table below lists warfarin alternatives. For the Consumer. Applies to warfarin: oral tablet. Along with its needed effects, warfarin may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. I have written on this matter intermittently in the last year or two as new alternatives to warfarin have become available for patients with atrial fibrillation. From The Doctors Desk: New Alternatives to Coumadin for Atrial Fibrillation Updated June 2015 Atrial fibrillation is a heart rhythm disturbance that affects up to 3% of the adult population but is found more frequently as people age. Warfarin Replacement? By Mike Bassett Today’s Geriatric Medicine Vol. 6 No. 6 P. 16. New atrial fibrillation drugs possess significant advantages over warfarin for reducing the risk of embolic events such as a stroke or peripheral embolism. Warfarin is the most widely prescribed anticoagulant (a drug which reduces the risk of blood clots forming) in the UK. Find out why you might take it, possible side effects, and what you need to know if you take warfarin. However, three new anticoagulants have recently been approved by the Food and Drug Administration: dabigatran (Pradaxa ®), rivaroxaban (Xarelto ®) and apixaban (Eliquis ®). This means that warfarin, Jantoven ® and Coumadin ® alternatives are now available for patients diagnosed with atrial fibrillation who need an anticoagulant.