Femara and Pregnancy - Success Rates Using Femara and Letrozole. Monthly chances for getting pregnant using letrozole are about the same as with using Clomid. Clomid is taken as a pill. This is unlike the stronger fertility drugs, which require injection. Clomid is also very effective, stimulating ovulation 80 percent of the time. What is Clomid and how does it work? Clomid is an oral medication that can be used to stimulate ovulation. It works by blocking estrogen receptors at the hypothalamus, which is an important hormonal control center for the body. Clomid is often a first medicine for infertility treatment. The goal of Clomid therapy in treating infertility is to induce ovulation. Pregnancy usually occurs during the first two months of infertility therapy with Clomid. Beating cancer takes more than medicine. That’s why we do much more than breakthrough research. We also o er free rides to chemo, a live 24/7 helpline, and free lodging near hospitals for people dealing with every type of cancer. We’re attacking from every angle. Clomid is often prescribed by primary care physicians or OB-GYNs before they refer a couple to see a fertility specialist for more specialized care. Clomid is commonly prescribed off-label to treat infertility and low testosterone (hypogonadism) in men. Clomid may be effective at treating azoospermia. How do you take Clomid for infertility? If your doctor has prescribed this popular fertility drug, you're probably curious about what to expect. Clomid or Serophene (J8499) Novarel (J0725) Each covered insemination related Ovulation Induction cycle is followed with a quantitative Beta HCG pregnancy test. Medical uses. Clomifene is useful in those who are infertile due to anovulation or oligoovulation. Evidence is lacking for the use of clomifene in those who are infertile without a known reason. In such cases, studies have observed a clinical pregnancy rate 5.6% per cycle with clomifene treatment vs. 1.3%–4.2% per cycle without treatment.