Though the overall occurrence of side effects is relatively low among women who take tamoxifen, the following side effects have been reported. Breastcancer.org is a registered 501(c)(3) nonprofit organization dedicated to providing information and community to those touched by this disease. Tamoxifen may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away: Increased bone or tumor pain; Pain or reddening around the tumor site Tamoxifen (Nolvadex), a hormone therapy drug, is used to treat breast cancers and to lower risk in women at high risk of breast cancer. Read about Tamoxifen side-effects here. Tamoxifen may cause cancer of the uterus (womb), strokes, and blood clots in the lungs. These conditions may be serious or fatal. Tell your doctor if you have ever had a blood clot in the lungs or legs, a stroke, or a heart attack. Natural Remedies For Tamoxifen Withdrawal Side Effects. If you are in the process of weaning yourself off of tamoxifen (and there are many reasons why you might want to do so) and need help with the resulting withdrawal side effects, this article shares some tried and true natural remedies to help you out. Harry Connick Jr.’s wife Jill Goodacre has been taking tamoxifen since her breast cancer surgery. Here are the facts on tamoxifen's side effects and Tamoxifen citrate tablets USP, a nonsteroidal antiestrogen, are for oral administration. Each film coated tablet contains Tamoxifen citrate15.2 mg or 30.4 mg equivalent to Tamoxifen 10 mg or 20 mg respectively. What other drugs will affect tamoxifen? Many drugs can interact with tamoxifen, and some drugs should not be used together. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Most doctors recommend taking tamoxifen at the same time each day. You should not take tamoxifen if you are breastfeeding, pregnant, trying to get pregnant, or if there is any chance that you could be pregnant.