• Digoxin is indicated for the treatment of congestive cardiac failure. • Digoxin may be used for certain supraventricular dysrhythmias, particularly atrial fibrillation. Memantine Hydrochloride Pharmacokinetics Absorption. Well absorbed following oral administration, with peak plasma concentrations attained in about 3–7 hours. 1 4 DIGITEK® (digoxin) Tablets, USP. DESCRIPTION. DIGITEK (digoxin) is one of the cardiac (or digitalis) glycosides, a closely related group of drugs having in common specific effects on the myocardium. Digoxin is used to treat heart failure, usually along with other medications. Learn about side effects, drug interactions, dosages, warnings, and more. In patients with atrial fibrillation (AF) and heart failure (HF) with or without systolic dysfunction, either rhythm control or rate control is an acceptable primary therapeutic option. Digoxin, sold under the brand name Lanoxin, is a prescription drug used to help treat arrhythmia (irregular heartbeat) and improve symptoms of fatigue caused by heart failure. An adverse drug reaction (ADR) is an injury caused by taking medication. ADRs may occur following a single dose or prolonged administration of a drug or result from the combination of two or more drugs. Be sure the patient is not on digitoxin instead of digoxin. Digitoxin is also an active component of digitalis leaf. The 2013 ACCF/HCA Guidelines for Management of Heart Failure suggest a therapeutic range of 0.5 -0.9 ng/mL for digoxin. Cardiac failure. Digoxin is indicated in the management of chronic cardiac failure where the dominant problem is systolic dysfunction. The therapeutic benefit of digoxin is greater in patients with ventricular dilatation. Uses. Digoxin is used to treat heart failure, usually along with other medications. It is also used to treat certain types of irregular heartbeat (such as chronic atrial fibrillation).