Compare Mirtazapine vs. Sertraline, which is better for uses like: Anxiety, Depression and Major Depression. Compare head-to-head ratings, side effects, warnings, dosages, interactions and patient reviews. Patients rated Mirtazapine and Sertraline evenly with 3.2/5. The patients rated as improved on sertraline reported better quality of life than the ones who improved on placebo. The authors of the study argued that the improvement achieved with sertraline is different and of a better quality than the improvement achieved with placebo. 1305 Braz J Med Biol Res 34(10) 2001 Mirtazapine versus fluoxetine in panic disorder any follow-up data. Outcomes were ana-lyzed by ANOVA for repeated measures. Hard to say. As you might know, there are many brands of anxiety. In my practice, Remeron tends to work well for people who are so anxious they can't sleep at night, as it combats anxiety and is sedating. Mirtazapine orally disintegrating tablet versus sertraline: a prospective onset of action study by Behnke K, Sogaard J, Martin S, Bauml J, Ravindran AV, Agren H, Vester-Blokland ED. Compare Mirtazapine vs Sertraline head-to-head for uses, ratings, cost, side effects, interactions and more. Mirtazapine rated 7.1/10 vs Sertraline rated 7.4/10 in overall patient satisfaction. Mirtazapine rated 7.1/10 vs Sertraline rated 7.4/10 in overall patient satisfaction. Compare Mirtazapine vs. Zoloft, which is better for uses like: Anxiety, Depression and Major Depression. Compare head-to-head ratings, side effects, warnings, dosages, interactions and patient reviews. Patients rated Zoloft 3.4/5 over Mirtazapine 3.2/5 in overall satisfaction. Compare Mirtazapine vs Zoloft head-to-head for uses, ratings, cost, side effects, interactions and more. Mirtazapine rated 7.1/10 vs Zoloft rated 7.4/10 in overall patient satisfaction. Sertraline is a 'mood lifter', mirtazapine calms & helps sleep. I think this is why they are often given together. Mirtazapine can make you very sleepy when you first start but that soon settles down. Mam was told to take it 30 mins before bed, which she does & she is sleeping better than she has in years. She is also calmer & happier.