I understand your aggitation. sucks really because it's the only anti depressent i've found that works for depression for me. it has to do with dopamine re-uptake inhibition. the others deal with seritonin and norepinephrine. my problem is dopamine and that is from years of opiate addiction. WELLBUTRIN XL®, the only extended-release bupropion with more than 15 years of experience in Major Depressive Disorder (MDD) and more than 10 years of experience in Seasonal Affective Disorder (SAD). I have been on a 150 mg of Wellbutrin for over a month now and was just increased to 300mg. I know I have depression and have finally resolved to the medication but with my teaching school year starting again soon- July, I can really feel the anxiety increasing. Bupropion, sold under the brand names Wellbutrin and Zyban among others, is a medication primarily used to treat major depressive disorder and to support stopping smoking. It is an effective antidepressant on its own, but is also used as an add-on medication in cases of incomplete response to first-line SSRI antidepressants. Although weight gain is a potential side effect of Wellbutrin, the medicine is more likely to cause weight loss. If you are taking Wellbutrin and weight gain does become a problem, be sure to talk with your healthcare provider. Compare prices, print coupons and get savings tips for Wellbutrin (Bupropion) and other Depression drugs at CVS, Walgreens, and other pharmacies. Prices start at $9.00 Wellbutrin is a prescription medication that is approved to treat depression. This eMedTV article explains how the medication works, highlights some of its potential side effects, offers tips on when and how to take it, and more. My experience is very similar. I was 125 lbs when I started taking Paxil for anxiety and gained about 40lbs over the course of 2 years. I started on Wellbutrin at the suggestion of my Dr. when I advised that I no longer wanted to take it due to the horrible weight gain. Wellbutrin and Memory Loss: learn more about Wellbutrin related memory loss and how to increase memory. Wellbutrin (bupropion) is an effective antidepressant (Thase, M 2005). It exists in instant release (IR), sustained release (SR) and extended release (XL) forms.