I am wondering the same thing. I went to the Minute Clinic yesterday for a UTI (urinary tract infection) and told the doctor that I also have a very sore throat and believe it is strep (which I have had many times and am very familiar with the symptoms). Common Questions and Answers about Macrobid for sore throat. macrobid. Is there anything I can do for a bad sore throat. I went to my gyn I had a uti he gave me meds macrobid and said it will also help my throat. But I don't see how plus I don't feel comfortable taking meds while I'm pregnant Is there anything I can do without meds ?for UTI and Sore Throat if not did anybody take MACROBID. It may help but it's not the best antibiotic for strep throat. Nitrofurantoin is more for bacteria causing urinary tract infections. This brand contains nitrofurantoin. It does not treat the strep throat. Doctors give trusted answers on uses, effects, side-effects, and cautions: Dr. Grim on will macrobid treat strep throat: It'll likely take care of the infection but it's not recommended as first or even second line use. There are reports of increasing resistance of group a strep to fluoroquinolones (cipro). Penicillin is still the first choice. If you have a sore throat, have the diagnosis confirmed with a quick test and properly treated. Many sore throats are viral and need no antibiotics. Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, expect. Can I use Nitrofurantoin for a strep throat infection - Answered by a verified Doctor We use cookies to give you the best possible experience on our website. By continuing to use this site you consent to the use of cookies on your device as described in our cookie policy unless you have disabled them. Most likely the initial throat infection was due to a garden variety respiratory virus, or was a strep throat despite the negative test for it, and has nothing to do with the mutual oral sex event. I am fairly certain I have strep (I have white spots on my very swollen tonsils, fever, extreme fatigue, throat so sore I can barely swallow a drink), but I do not have health insurance and can not afford a doctor visit right now.