Pain is the most obvious, and sometimes the most difficult, symptom of fibromyalgia. Other symptoms like fatigue, poor concentration, and depression or anxiety can also have a big effect on your life. Duloxetine, sold under the brand name Cymbalta among others, is a medication used to treat major depressive disorder, generalized anxiety disorder, fibromyalgia, and neuropathic pain. It is taken by mouth. Lack of Motivation? Depression Could Be the Cause If you're experiencing a lack of motivation to do what you enjoy, it's one of several signs of depression or other mood disorders. Antidepressant Warnings: There have been 151 warnings from 11 countries (Australia, Canada, Denmark, Germany, Ireland, Italy, Japan, New Zealand, Russia, United Kingdom and United States) and the European Union warning that antidepressants cause harmful side effects. by Steven Scanlan, M.D. Palm Beach Outpatient Detox Boca Raton, FL (561) 901-0040. This discussion is addressed to providers as well as their patients who have become dependent on Suboxone (buprenorphine plus naloxone) or Subutex (buprenorphine alone) and who are seeking knowledge and hopefully wisdom about its use and abuse. Cymbalta official prescribing information for healthcare professionals. Includes: indications, dosage, adverse reactions, pharmacology and more. This update on the Cymbalta lawsuit settlement was first published on NationalPainReport.com. It is being republished here with permission from the editor. Initially, 20 mg PO twice daily (40 mg/day) or 60 mg/day PO as a single dose or in 2 divided doses (i.e., 30 mg PO twice daily). An alternate regimen is 30 mg/day for 1 week followed by an increase to 60 mg/day. User Reviews for Cymbalta to treat Chronic Pain. The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care. Learn about Cymbalta (Duloxetine Hcl) may treat, uses, dosage, side effects, drug interactions, warnings, patient labeling, reviews, and related medications.