WARNING. FETAL TOXICITY. When pregnancy is detected, discontinue AVAPRO as soon as possible. Drugs that act directly on the renin-angiotens in system can cause injury and death to the developing fetus [see WARNINGS AND PRECAUTIONS]. Avapro (irbesartan) belongs to a group of drugs called angiotensin II receptor antagonists. Irbesartan keeps blood vessels from narrowing, which lowers blood pressure and improves blood flow. Avapro ® is a prescription medicine that has been licensed to treat several conditions related to the heart and blood vessels. It is part of a class of drugs called angiotensin II receptor blockers, or ARBs for short. AVAPRO® Tablets. Irbesartan. Consumer Medicine Information. What is in this leaflet. Read this leaflet carefully before taking AVAPRO. This leaflet answers some common questions about AVAPRO. Hypertension. Avapro ® is indicated for the treatment of hypertension, to lower blood pressure. Lowering blood pressure lowers the risk of fatal and non-fatal cardiovascular (CV) events, primarily strokes and myocardial infarction. Irbesartan is classified as FDA pregnancy risk category D. When used during pregnancy, drugs that affect the renin-angiotensin system (e.g., ACE inhibitors, angiotensin II receptor antagonists) can cause fetal death or injury such as hypotension, neonatal skull hypoplasia, anuria, reversible or irreversible renal failure and death. Goji is a plant that grows in the Mediterranean region and parts of Asia. The berries and root bark are used to make medicine. Goji is used for many conditions including diabetes, weight loss, improving quality of life, and as a tonic, but there is no good scientific evidence to support any of these uses. Irbesartan is the generic form of the brand-name drug Avapro, which is used to treat high blood pressure. It's also used to treat kidney disease that's caused by diabetes, as well as heart failure. Irbesartan is used to treat high blood pressure (hypertension) and to help protect the kidneys from damage due to diabetes. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. Irbesartan (Avapro), a drug used to treat high blood pressure and diabetic nephropathy (kidney disease). Information includes side effects, dosage, and pregnancy safety information.