Table III presents some pharmacologic options for pain relief. Drug therapy for amelioration of pain symptoms includes acetaminophen, nsaid s such as naproxen, mild opiates, strong opiates, and glucosamine 23. Breast cancer patients taking Arimidex may get pain relief from vitamin D By Gwen Ericson March 30, 2006 January 13, 2016 Click to share on Facebook (Opens in new window) The pain from Arimidex was almost exclusively on my feet, and usually a constant, even waking me from sleep. It interfered with my favorite form of exercise, walking 2 miles a day. It interfered with my favorite form of exercise, walking 2 miles a day. All the women had muscle and bone pain that began after they started taking Arimidex. All the women took over-the-counter supplements of calcium (1,000 mg) and vitamin D3 (400 IU) each day. All the women took over-the-counter supplements of calcium (1,000 mg) and vitamin D3 (400 IU) each day. My mother who is 77, has metastatic breast cancer.she was diagnosed in 1986, treated with surgery and Tamoxifen.she had mets to the breast bone last year treated. Aromatase inhibitors (AIs) - those drugs we love to hate Whether you're taking Femara, Arimidex, or Aromasin, there's a good chance you're experiencing a common side effect, arthralgia - joint pain. Along with its needed effects, a medicine may cause some unwanted effects. Although not all of. pains in the stomach, side, or abdomen, possibly radiating to the back. persistent crusting or. sore on the skin of the breast that does not heal. unexplained. I'm also on arimidex and also have serious joint pain in knees and hips. Oncologist said arimidex does not cause joint pain. She is incorrect. We use cookies to ensure that we give you the best experience on our website. More about our cookies My MRI was negative. I switched to Arimidex one month ago. I am experiencing thesame musclular skeletal pain and joint and back pain. It is especially bad at night and first thing in the morning.