Premature ejaculation is by far the biggest complaint that men have about their sexual performance. After studying data gathered by the National Health and Social Life Survey, sociologist Edward. Dear Alice, I know that you've briefly addressed the use of Prozac and its effects on the male libido, but I was wondering if you could comment in a bit more detail on its use by men to help them maintain a strong libido and increased control of release. All 100 men complained of secondary premature ejaculation reporting previous satisfactory ejaculatory control with no report of extra-vaginal ejaculation. Mean frequency of coitus was not statistically different among the 3 groups during the one month treatment period. Fluoxetine can sometimes be prescribed off-label to treat premature ejaculation. This part of the eMedTV library further explores premature ejaculation and fluoxetine, and explains how the medication works to help delay ejaculation. Premature ejaculation is underdiagnosed and undertreated because of a reluctance to discuss it, by both patient and physician. A thorough medical history, including pertinent sexual history and physical examination, can often establish the diagnosis of premature ejaculation. Can Prozac Treat Premature Ejaculation? A physician may prescribe Prozac for patients with premature ejaculation because of a curious side effect it causes in men. SSRIs have a tendency to delay an orgasm, much to the point that it allows a man to enjoy sex longer, but can still eventually achieve climax and ejaculation. Treatment for premature ejaculation consists of psychological counselling,medications like SSRI’s like Prozac, Zoloft, Celexa,5HTP and clomipramine.Pls discuss these treatment options with a urologist. Here’s how to use Prozac for premature ejaculation… First of all, Prozac is the brand name for fluoxetine. I think it’s the oldest, and the best known of all SSRI antidepressants. Most men don't seek medical help for this problem—partially because they may be embarrassed or perhaps because they are unaware that effective treatments are available. But premature ejaculation.