Do not take prednisone if you have tuberculosis (active or inactive), shingles or other herpes infection of eyes, lips, or genitals. You should not be vaccinated against any infectious disease while you are on prednisone especially live polio vaccine. Allergy skin tests and TB skin tests will usually be invalid while you are on prednisone. A small number of patients on prednisone develop yeast. Medical Advice. It is not our intention to serve as a substitute for medical advice and any content posted should not be used for medical advice, diagnosis or treatment. Continued. For the study, Leuppi's team randomly assigned more than 300 patients suffering from an acute COPD exacerbation to daily doses of prednisone for either five or 14 days. Get the facts on steroids for COPD here. These drugs will help reduce the inflammation in your lungs caused by flare-ups. Also learn about side effects, necessary precautions, alternatives, and more. Exacerbations of chronic obstructive pulmonary disease (COPD) have a negative effect on patients in terms of mortality, 1,2 health related quality of life, and decline in lung function including huge socioeconomic costs on healthcare resources. Do you have COPD or asthma? That could be the problem. I know from another forum that some people with COPD have to take That could be the problem. I know from another forum that some people with COPD have to take Prednisone on a regular basis. If you take prednisone on a daily basis, for a long period of time, it can cause adrenal gland suppression. This is when your body stops producing cortisol by itself. This is when your body stops producing cortisol by itself. Archives Is Prednisone a Friend or Foe? Probably just about everyone who reads this monthly Newsletter knows about prednisone. Prednisone is in a class of drugs called corticosteroids, related to the cortisone group of medications. I use Prednisone to recover from a cold, else it will take 6 to 8 wks to recover EVERY TIME, so I start Prednisone after 4 days at most. Doc says 2x/yr at most to avoid bone problems. One time I had to do 2 courses of Pred so now am prescribed 7 days. With these meds I am hoping for another 15 years, and maybe by then they'll be using stem cells to repair lungs! Hint to COPD sufferers (and all.