Is Tretinoin An Effective Treatment For Acne? Topical tretinoin for acne is the over-the-counter (or, more often, over the Internet) form of the best-known acne drug Retin-A. Skinderma Pro - 'Professional Strength' Scar and. Stretch Mark Serum (Liquid Concentrate) - 11 ml Tretinoin or Retin-A is the topical form of retinoic acid. It is commonly used for acne. Tretinoin also has rejuvenative effects on the skin namely compacting the epidermis so skin looks and feels smoother, increasing collagen content so that skin has less fine lines and wrinkles, and minimizing brown spots to provide more even coloration. Psoriasis plaque and scarring may lead to feelings of insecurity. Minimizing the appearance of psoriasis scars may help to lessen the “psoriasis stigma” and help boost your confidence. Retin-A (tretinoin) for Acne: I'm in my early 20s and have been applying Retin-A gel once a night for over a year now. Before starting the gel I had what I would describe as moderate acne. Reviews and ratings for tretinoin when used in the treatment of acne. 365 reviews submitted. Tretinoin cream is a medication used to treat acne. According to Drugs.com, it is a vitamin A derivative that induces skin-cell turnover and allows the skin cells to stay separated. Does Tretinoin Uncover Previously Unseen Pitted Acne Scars? I have been using tretinoin for the past eight months, and about two months ago I started noticing more indented acne scars, pits on my face. For years, I had an acne problem. While the acne cleared up, it did leave some scarring. My doctor suggested using Retin-A (Tretinoin). I have a few spots on my face with heavy scarring, but most of the scars on my face aren't as severe. Tretinoin Cream, which is also known by its brand names Retrieve Cream and Retin A, is one of the most popular revitalization topical creams available on the market today.