When first beginning treatment with trazodone, dosing guidelines generally call for 150 mg a day. Depending on your response to the medication, this amount can be increased up to 400 mg per day (or 600 mg for those who are being treated in the hospital). Doctors give trusted answers on uses, effects, side-effects, and cautions: Dr. Melton on how to take trazodone for sleep: While the onset of action of Diphenhydramine (active ingredient in zzzquil) is less than 10 minutes, the peak effect is more like 60-90 minutes. It definitely helps with situational anxiety during the day. Be careful if you get too drowsy though, at first. Be careful if you get too drowsy though, at first. Share this post Hi! So like the post states, I have been prescribed Bupropion (150mg) twice a day for ADD. My doctor is currently waiting on my EKG results to see. I am experimenting with taking 50 in the pm and 50 in the am, but feel I tired and out of fuzzy during the day. My daytime anxiety is improving, but I find it hard to focus. My daytime anxiety is improving, but I find it hard to focus. Interesting to read. I’ve been taking Trazodone for 10 years now and it works ‘like a dream!’ — pun intended. I get the solid 8 hours of sleep that I need, no hangovers, no spooky/dysphoric dreams, no headaches, nothing but great restful sleep. buy online without a doctor is prescription. ★★★ taking trazodone during the day ★★★ Free pills with every order! Free shipping, quality, privacy, secure. Badwolf, sorry to hear your feeling so tired. Yes I would say it most certainly is normal to feel tired during the day with trazadone use, one of the reasons I try to sleep without it if I can.