Oxycodone is usually swallowed but is sometimes injected or used as a suppository. To prevent OxyContin ® tablets being injected by people who misuse them, they were reformulated in 2014. The tablets are now resistant to crushing and become a thick gel when added to water. While surfing the Internet one evening, I stumbled upon a few Usenet articles regarding rectal administration of prescription opioid pain-killers. Taking Dilaudid (hydromorphone suppository) within 14 days of those drugs can cause very bad high blood pressure. If you are taking any of these drugs: Linezolid or methylene blue. If you are breast-feeding or plan to breast-feed. Oxycodone extended-release capsules or tablets should only be used by patients who have already been taking narcotic pain medicines, also called opioids. These patients are called opioid-tolerant. If you are uncertain whether or not you are opioid-tolerant, check with your doctor before using this medicine. Oxycodone, a semisynthetic opioid, is generally indicated for relief of moderate to severe pain and is the main ingredient in prescription painkillers OxyContin and Percocet. Morphine rectal comes as a suppository to insert in the rectum. It is usually inserted every 4 hours. Use rectal morphine at around the same times every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use morphine exactly as directed. there is an overwhelming need to continue taking the drug or similar drugs and to increase the dose. Studies indicate that diets containing large amounts of non-absorbable polysaccharides, such as cellulose, might decrease absorption of calcium, PATIENT MEDICATION INFORMATION Supeudol Oxycodone Hydrochloride USP Suppositories/Tablets 5 mg and 10 mg Supeudol Oxycodone Hydrochloride Suppositories 10 mg and 20 mg Read this carefully before you start taking Supeudol and each time you get a refill. This leaflet is a summary and will not tell you everything about this drug. Talk to your healthcare professional about your medical condition. Oxycodone has a risk for abuse and addiction, which can lead to overdose and death. Oxycodone may also cause severe, possibly fatal, breathing problems. Proladone Suppositories is a brand of medicine containing the active ingredient Oxycodone. Find out about side effects, who can take it and who shouldn’t use.