I started on the zoloft/sertraline and went through a couple of weeks of no sleep, crying, obsessive analysis of myself and my treats. A milestone for me was I actually took a week of mertazapine which gave me 2 nights fantastic sleep. After that I began to regain perspective. I dropped the mertazapine because it seemed more intrusive in the. Zoloft and other antidepressants can have this effect. For me, it increased my anxiety and I eventually stop taking it. There's always the chance that this is something that will happen only in the adjustment period, but if it continues for too long, then talk to your doctor about switching you. Zoloft and Anxiety Crying and Pain Zoloft and Depression Crying and Depression Zoloft and Prozac Crying and Tiredness Zoloft and Paxil Crying and Feeling Sick Zoloft and Lexapro Crying and Anger Treato does not review third-party posts for accuracy of any kind, including for medical diagnosis or treatments, or events in general. If you are currently taking Zoloft (or a generic alternative) and are thinking about stopping or weaning off, but you're wondering if the dose-reduction process may actually be causing depression or anxiety attacks, please read on. Note: Most people retain the active ingredient “Sertraline” for up to 6 days and its metabolite desmethylsertraline for over 2 weeks after stopping. As a result, symptoms may emerge with increased severity within 1-3 weeks after stopping. Zoloft Withdrawal Symptoms: Extensive List Stopping Zoloft altogether gives different effects to the people. One of its reactions is you will be crying about the small things. Even, they don’t bother you at all. Beside crying a lot, you likely feel helpless, sorrow, and alone. This overwhelming sadness significantly seeps into your mind and bones. Because Zoloft leaves your body so quickly, stopping it too abruptly can cause discontinuation syndrome to develop. Among the symptoms that may be experienced are nausea, tremor, dizziness, muscle pains, weakness, insomnia, and anxiety.