Let me first say, I don’t hate Metformin for women with PCOS. For some women it really does help spur ovulation, control blood sugar and help with some weight management but….it’s not without its share of issues.And it’s definitely not the magic bullet for weight loss – although it’s usually presented that way. New research is starting to compare the benefits of inositol to metformin in women with PCOS. The results may surprise you! My gyno prescribed metformin 500 mg 2 x day for PCOS. He said it was an anti-diabetic but that it is also taken for PCOS. I have had a hard time managing my weight and he thought that it would help. A nutrition supplement called Ovasitol can really help women with PCOS? I’ll admit, I was skeptical too-until I tried it. I used to believe that most women with PCOS can get their needs met through food and didn’t need to take supplements. USUAL DOSE: 500 mg PO once daily with the evening meal. In the geriatric adult, do not initiate therapy if 80 years old or older unless normal renal function is documented. Metformin side effects, use for diabetes treatment, dosage November 19 2018 by Ray Sahelian, M.D. Metformin is a drug used to treat type 2 diabetes mellitus. This eMedTV segment explains that the recommended starting dosage of metformin is 500 mg twice daily. The maximum dose of the drug will vary depending on several factors, such as age and other medications you are taking. The biggest problem many people have with Metformin is that it causes such misery when it hits their stomachs that they can't keep taking it even though they know it is the safest and most effective of all the oral diabetes drugs. Metformin has been used to treat diabetes since the late 1950s. It is now on the World Health Organisation's List of Essential Medicines needed for a basic health care system. User Reviews for Metformin. Also known as: Fortamet, Glucophage, Glucophage XR, Glumetza, Riomet. The following information is NOT intended to endorse drugs or recommend therapy.