This provides updated information to the FDA Drug Safety Communication: FDA warns about serious risks and death when combining opioid pain or cough medicines with benzodiazepines; requires its. Below is a fact sheet about Flexeril, including side effects, generic information, dosage and storage information, and more. Learn about Skelaxin (Metaxalone) may treat, uses, dosage, side effects, drug interactions, warnings, patient labeling, reviews, and related medications. Common Muscle Relaxant Medications. Muscle relaxants usually used to treat back pain and other types of pain include: Baclofen Muscle tightness and muscle spasms, including those related to spine injuries, are eased with baclofen. i began to have excruciating low back pain and my leg still hurt. The surgeon passed me off to pain management and said i fell into the six percent failure rate, the one he never told me about. ** Originally posted by Kentucky_Girl ** tramadol is one of the synthetic pain killers so it's an opiod not a hyrocodone based product. it's the weakest of the pain killers. METAXALONE is a muscle relaxer. It is used to treat pain and stiffness in muscles caused by strains, sprains, or other injury. The lowest GoodRx price for the most common version of generic Skelaxin is around $43.70, 69% off the average retail price of $143.89. What are some side effects that I need to call my doctor about right away? WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. The value of knowing the side effects of neck or back pain medications is that it enables you to make informed choices. This is called weighing the risk to benefit ratio. Flexeril (cyclobenzaprine) is a muscle relaxant indicated as an adjunct to rest and physical therapy for relief of muscle spasm associated with acute, painful musculoskeletal conditions.