Simvastatin improves the sexual health-related quality of life in men aged 40 years and over with erectile dysfunction: Additional data from the erectile dysfunction and statin trial Can simvastatin improve erectile function and health-related quality of life in men aged ≥40 years with erectile dysfunction? Results of the Erectile Dysfunction and Statins Trial [ISRCTN66772971] Results of the Erectile Dysfunction and Statins Trial [ISRCTN66772971] At the end of the seventh month, all patients from the simvastatin group progressed to mild erectile dysfunction, compared with only 83% in the placebo group. Finally, there was no statistically significant difference in penile erection after intake of simvastatin or placebo ( Mastalir et al, 2011 ). Film-Coated Tablet. Simvastatin 40 mg tablets, are brick red coloured, oval shaped, biconvex, film-coated tablets, debossed with '40' on one side and breakline on the other side, containing Simvastatin 40 mg. Frequency not reported: Cognitive impairment, cranial nerve dysfunction, tremor, vertigo, memory loss, paraesthesias, peripheral neuropathy, peripheral nerve palsy Renal Frequency not reported : Myoglobinuria, acute renal failure secondary to rhabdomyolysis [ Ref ] Methods. This is a double blind randomised controlled trial of 40 mg simvastatin or placebo given once daily for six months to men over forty years with untreated erectile dysfunction, who were not at high cardiovascular risk and were not on anti-hypertensive or lipid-lowering medication. 173 eligible men were recruited from 10 general. I am 71 years old and have been on simvastatin 20 mg for at least 8 years and have developed ED within the last 18 months. My Dr. prescribed Viagra from the Canadian pharmacies and they are legit. My Dr. prescribed Viagra from the Canadian pharmacies and they are legit. Erectile dysfunction (ED) is a condition marked by the inability to achieve or maintain an erection. The risk increases with age, according to the National Institute of Diabetes and Digestive and. untreated erectile dysfunction given 40 mg simvastatin for six months. Trial registration: Current Controlled Trials ISRCTN66772971. Keywords: Erectile dysfunction, Statins, Sexual health quality of life, Randomised controlled trial Can simvastatin improve erectile function and health-related quality of life in men aged≥40 years with erectile dysfunction? Results of the erectile dysfunction and statins trial. Results of the erectile dysfunction and statins trial.