If Prilosec OTC takes a few days to take effect, can I take more each day to make it work faster? No. Prilosec OTC is not intended for immediate relief of occasional heartburn. Prilosec OTC may. Prilosec OTC was the first over-the-counter PPI on the market and continues to provide heartburn relief to frequent heartburn sufferers with its trusted formula. It has been the 1 Doctor and Gastroenterologist recommended heartburn medicine for 15 straight years.^ Join more than 30 million heartburn sufferers that have tried Prilosec OTC for their heartburn.** Prilosec (omeprazole) is a proton pump inhibitor that treats severe stomach acid-related conditions like GERD. Common Prilosec side effects include headache, stomach pain and nausea. Long-term Prilosec use has been linked to kidney damage, bone fractures and other dangerous side effects. Unlike prescription Prilosec, Prilosec OTC is safe to. Prilosec side effects. Get emergency medical help if you have signs of an allergic reaction to Prilosec: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using Prilosec and call your doctor at once if you have: severe stomach pain, diarrhea that is watery or bloody; new or unusual pain in your wrist, thigh, hip. Find patient medical information for Prilosec OTC oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Omeprazole, sold under the brand names Prilosec and Losec, among others, is a medication used in the treatment of gastroesophageal reflux disease (GERD), peptic ulcer disease, and Zollinger–Ellison syndrome. It is also used to prevent upper gastrointestinal bleeding in people who are at high risk. Omeprazole is a proton-pump inhibitor (PPI) and its effectiveness is similar to other PPIs. Prilosec OTC can stop frequent heartburn before it begins. With one pill a day, you can get 24-hour heartburn relief.* Prilosec OTC became the first and original OTC frequent heartburn medication in 2003. Find patient medical information for Prilosec oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Prilosec OTC is a proton pump inhibitor (PPI) that can block heartburn at the source, so you don’t get heartburn in the first place. Prilosec OTC’s delayed-release formula helps it pass through the tough stomach acid, turning down acid production. Some other heartburn relief treatments only neutralize the stomach acid and provide less relief (less than 24 hours), while Prilosec OTC’s. Overview of Omeprazole (Prilosec®) for Dogs and Cats Omeprazole, commonly known by the brand name Prilosec®, is used in the treatment and prevention of stomach (gastric) and intestinal ulcers in dogs and cats.; The newest drugs used in the treatment of ulcers and heartburn (acid reflux from the stomach) belong to a class of drugs called proton pump inhibitors.