Nifedipine is a prescription drug used to treat high blood pressure and control chest pain. It’s sold under the brand names Procardia XL, Adalat CC, and others, and generic versions are available. Side Effects. Drug information provided by: IBM Micromedex. Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Consumer information about the medication NIFEDIPINE - ORAL (Procardia), includes side effects, drug interactions, recommended dosages, and storage information. Read more about the prescription drug NIFEDIPINE - ORAL. Find information about common, infrequent and rare side effects of Nifedipine Oral. SIDE EFFECTS Adverse Experiences. The incidence of adverse events during treatment with Adalat CC in doses up to 90 mg daily were derived from multi-center placebo-controlled clinical trials in 370 hypertensive patients. In fact, of all the calcium channel blockers, nifedipine is perhaps the worst offender when it comes to this side effect. Almost all patients taking nifedipine develop this gum growth to some extent, but the degree to which it develops is highly variable. Though it has various side effects, gingival enlargement is the most attended side effect which is of great importance in dentistry. Nifedipine-induced gingival enlargement was first reported in 1984.[ 2 ] Side Effects. Dizziness, flushing, weakness, swelling ankles/feet, constipation, and headache may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. Along with its needed effects, nifedipine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. -Doses should be gradually decreased and patients should be monitored for side effects. Precautions Safety and efficacy have not been established in patients younger than 18 years.