Misoprostol is currently only approved by the Food and Drug Administration (FDA) for the prevention and treatment of gastric ulcers resulting from chronic administration of nonsteroidal anti-inflammatory drugs (NSAIDS) more info. Prevent complications. Use of misoprostol in obstetrics and gynaecology. The correct dosage varies greatly according to gestation, indication and route of. Find patient medical information for misoprostol oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Misoprostol dosage for abortion. You will need 12 pills of Misoprostol. If it is difficult to obtain 12 pills, you can choose to proceed with only 8 pills of Misoprostol, but the effectiveness will be reduced, and you should get in touch with our counselors. Then you take the second medicine, misoprostol, either right away or up to 48 hours later. This medicine causes cramping and bleeding to empty your uterus. It’s kind of like having a really heavy, crampy period, and the process is very similar to an early miscarriage. If you don’t have any bleeding within 24 hours after taking the second medicine, call your nurse or doctor. Your doctor or.