I have been taking lyrica (two 75 mg per day) for years for treatment of spinal stenosis. That and muscle relaxants (methocarbamol) help me get thru the night. Ive been on methocarbamol for years 750mg 4 x daily, they did not cause me any drowsiness or anything luckily! However since my second spinal surgery in october past my gp has doubled my dose so now on 1500mg 4 x daily and again thankfully has not affected mye in any negative way. I would agree to try one about an hour before you go to bed to see how they affect you and you can decide from. How Does Methocarbamol Work? It is not clear exactly how this medication helps to relieve muscle spasms. However, it is known to work mostly in the central nervous system (the brain and the spinal cord), not directly on the muscles. Summary. Spinal column stenosis is found among people who take Methocarbamol, especially for people who are female, 50-59 old also take medication Cymbalta, and have Breast cancer. Robaxin-750 (methocarbamol): I haven't taken this too long. I know enough that this like many drugs, are not magic pills. I have spinal stenosis due to 3 herniated disks and degenerative disk disease. Is Methocarbamol helpful for Spinal Stenosis? can Methocarbamol cause Spinal Stenosis? Methocarbamol is mentioned in 17 posts about Spinal Stenosis. - Page 2 Summary. Lumbar spinal stenosis is found among people who take Methocarbamol, especially for people who are female, 60+ old also take medication Oxycodone, and have Blood pressure management. Robaxin-750 (methocarbamol) for Muscle Spasm: I haven't taken this too long. I know enough that this like many drugs, are not magic pills. I have spinal stenosis due to 3 herniated disks and degenerative disk disease. Methocarbamol reduces nerve impulse transmission from spinal cord to skeletal muscle, providing pain relief for musculoskeletal conditions. Carisoprodol (Soma) Carisoprodol is a short-acting. Spinal stenosis refers to the narrowing of an area of the spine, often involving the canals through which nerves run. A person with this condition may have symptoms such as pain or numbness in the legs or shoulders as a result of the pressure put on the spinal cord.