especially from Pleurotus sp. which is used as a SCP producer. Production of Lovastatin Using submerged fermentation Many researches are being carried out for the production of lovastatin in submerged fermentation process using various microbes. Mainly in submerged fermentation process, the physico-chemical parameters were optimized for the better yield of lovastatin [27]. Genetically modified. Production and Purification of Statins from Pleurotus ostreatus (Basidiomycetes) Strains Julio Alarco´n*, Sergio A´ guila, Patricia Arancibia-Avila, Oscar Fuentes, Production of lovastatin by Pleurotus ostreatus Lovastatin is one of the earlier statin drugs, which is effective for the treatment of hypercholesterolemia, as an inhibitor of the HMG-CoA reductase. The present work was undertaken to determinate lovastatin production by Pleurotus ostreatus in fruiting bodies and its production on different fermentation media. We use cookies to make interactions with our website easy and meaningful, to better understand the use of our services, and to tailor advertising. The types of carbon source and nitrogen source used as well as the C:N ratio in the medium influenced lovastatin production by Pleurotus ostreatus. Home › Forums › ILM-E-GHAIB › Production of lovastatin by pleurotus ostreatus This topic contains 0 replies, has 1 voice, and was last updated by pocboetihau1992 1 month, 3 weeks ago. Viewing 1 post (of 1 total) Author Posts January 16, 2019 at 10:13 am 79196 Reply pocboetihau1992Participant CLICK HERE CLICK HERE CLICK HERE CLICK […] Lovastatin Production by Pleurotus ostreatus: Effects of the C:N Ratio Julio Alarco´n* and Sergio A´ guila Departamento de Ciencias Ba´sicas, Facultad de Ciencias, Universidad del Bı´oBı´o, Chilla´n, Lovastatin is also naturally produced by certain higher fungi, such as Pleurotus ostreatus (oyster mushroom) and closely related Pleurotus spp. Research into the effect of oyster mushroom and its extracts on the cholesterol levels of laboratory animals has been extensive, although the effect has been demonstrated in a very limited number of human subjects. Screening of different fungi for production of lovastatin Riya Dhar, Gourab Basu Choudhury, Vinod Kumar Nigam* Department of Bio-Engineering, Birla Institute of Technology, Mesra, Ranchi-835215, Jharkhand, India Lovastatin is a fungi-derived secondary metabolite with various applications within health and agro industries. • Industrial production is done using Aspergillus terreus strains.