Appendix to: Bailey DG, Dresser G, Arnold JMA. Grapefruit and medication interactions: forbidden fruit or avoidable consequences? CMAJ 2012; DOI:10.1503/cmaj.120951. Lorazepam (merknaam: Temesta) is een geneesmiddel van de klasse der benzodiazepines. Deze middelen kenmerken zich door vijf effecten die ook door lorazepam in wisselende mate gedeeld worden: anxiolytisch, anterograde amnesie, sedatief/hypnotisch, anticonvulsief en spierrelaxerend. Het middel heeft een korte tot middellange werkingsduur. Indicaciones y acción terapéutica. El lorazepam está indicado para el manejo del trastorno de ansiedad y para el alivio a corto o largo plazo de sus síntomas. Lorazepam Concentrate official prescribing information for healthcare professionals. Includes: indications, dosage, adverse reactions, pharmacology and more. Bioavailability and pharmacokinetics of lorazepam after intranasal, intravenous, and intramuscular administration Prediction of the human oral bioavailability by using in vitro and in silico drug related parameters in a physiologically based absorption model Lorazepam official prescribing information for healthcare professionals. Includes: indications, dosage, adverse reactions, pharmacology and more. Additionally, lorazepam’s metabolism is less reliant on hepatic function — unlike chlordiazepoxide and diazepam, which undergo both hepatic oxidation and glucuronidation, lorazepam only undergoes hepatic glucuronidation. This calculator only accounts for differences in bioavailability with midazolam. Other dosage forms, with a bioavailability of 90%, are assumed to have complete bioavailability for calculation purposes. Lorazepam (v Sloveniji na tržišču pod zaščitenima imenoma Loram in Lorsilan) je benzodiazepinska učinkovina z anksiolitičnim, pomirjevalnim/uspavalnim.